About Help FAQ

Symbol
Name
ID

Sox2
SRY (sex determining region Y)-box 2
MGI:98364

Phenotype annotations related to endocrine/exocrine glands

Darker colors indicate more annotations

Human Phenotypes	Anterior pituitary hypoplasia	Hypogonadotropic hypogonadism
Disease(s) Associated with SOX2	Anterior pituitary hypoplasia	Hypogonadotropic hypogonadism
syndromic microphthalmia 3

Mouse Phenotypes

abnormal salivary gland morphology

abnormal Ebner's gland morphology

absent anterior lingual gland

absent palatine gland

abnormal pituitary gland morphology

abnormal adenohypophysis development

bifurcated Rathke's pouch

decreased somatotroph cell number

small adenohypophysis

abnormal seminiferous tubule morphology

small testis

Availability

Mouse Genotype

Sox2^tm1Rlb/Sox2⁺

Sox2^tm2Lpev/Sox2^tm3Lpev

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23